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1

The essential role of the Cu(II) state of Sco in the maturation of the CuAcenter of cytochrome oxidase: evidence from H135Met and H135SeM variants of theBacillus subtilisSco

Gnana S. Siluvai, Michiko Nakano, Mary Mayfield, Ninian J. Blackburn

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2011

Language:

english

File:

PDF, 773 KB

english, 2011

2

Anatomy of a Red Copper Center: Spectroscopic Identification and Reactivity of the Copper Centers of Bacillus subtilis Sco and Its Cys-to-Ala Variants

Siluvai, Gnana S., Mayfield, Mary, Nilges, Mark J., DeBeer George, Serena, Blackburn, Ninian J.

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 1.97 MB

english, 2010

3

Modulating the copper–sulfur interaction in type 1 blue copper azurin by replacing Cys112 with nonproteinogenic homocysteine

Clark, Kevin M., Yu, Yang, van der Donk, Wilfred A., Blackburn, Ninian J., Lu, Yi

Journal:

Inorganic Chemistry Frontiers

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

4

H135A Controls the Redox Activity of the Sco Copper Center. Kinetic and Spectroscopic Studies of the His135Ala Variant of Bacillus subtilis Sco

Siluvai, Gnana S., Nakano, Michiko M., Mayfield, Mary, Nilges, Mark J., Blackburn, Ninian J.

Journal:

Year:

2009

Language:

english

File:

PDF, 3.46 MB

english, 2009

5

A Multinuclear Copper(I) Cluster Forms the Dimerization Interface in Copper-Loaded Human Copper Chaperone for Superoxide Dismutase †

Stasser, Jay P., Siluvai, Gnana S., Barry, Amanda N., Blackburn, Ninian J.

Journal:

Year:

2007

Language:

english

File:

PDF, 355 KB

english, 2007

6

Structural Studies of Copper(I) Complexes of Amyloid-β Peptide Fragments: Formation of Two-Coordinate Bis(histidine) Complexes

Richard A. Himes, Ga Young Park, Gnana Sutha Siluvai, Ninian J. Blackburn, Kenneth D. Karlin

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 393 KB

english, 2008

7

Structural Studies of Copper(I) Complexes of Amyloid-β Peptide Fragments: Formation of Two-Coordinate Bis(histidine) Complexes

Richard A. Himes, Ga Young Park, Gnana Sutha Siluvai, Ninian J. Blackburn, Kenneth D. Karlin

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 393 KB

english, 2008

8

Chemistry and spectroscopy of copper monooxygenases

Ninian J. Blackburn, Brian Reedy, Eilleen Zhou, Robert Carr, Steven J. Benkovic

Journal:

Journal of Inorganic Biochemistry

Year:

1992

Language:

english

File:

PDF, 103 KB

english, 1992

9

Copper-O22 reactivity. Involvement of oxodicopper(II) in amine oxidations and reduction of O2 using porphyrin-iron(II) and copper(I)

Kenneth D. Karlin, Qin-fen Gan, Alaganandan Nanthakumar, Stephen Fox, Natarajan Ravi, Boi Hanh Huynh, Robert D. Orosz, Edmund P. Day, Karl S. Hagen, Ninian J. Blackburn

Journal:

Journal of Inorganic Biochemistry

Year:

1993

Language:

english

File:

PDF, 89 KB

english, 1993

10

Isocyanide complexes of copper(I) proteins

Brian T. Reedy, Gang Zhao, Ninian J. Blackburn

Journal:

Journal of Inorganic Biochemistry

Year:

1993

Language:

english

File:

PDF, 73 KB

english, 1993

11

A Tale of Two Metals

Ninian J. Blackburn

Journal:

Chemistry & Biology

Year:

2010

Language:

english

File:

PDF, 190 KB

english, 2010

12

EXAFS studies of copper and zinc in metallothionein and bovine superoxide dismutase

Ian Ross, Norman Binstead, Ninian J. Blackburn, Ian Bremner, Gregory P. Diakun, Samar S. Hasnain, Peter F. Knowles, Milan Vašák, C.David Garner

Journal:

Inorganica Chimica Acta

Year:

1983

Language:

english

File:

PDF, 178 KB

english, 1983

13

X-ray absorption studies of copper chaperones

Ninian J. Blackburn, Martina Ralle, Svetlana Lutsenko, Jack Kaplan, John Eisses, Jay Stasser

Journal:

Journal of Inorganic Biochemistry

Year:

2003

Language:

english

File:

PDF, 165 KB

english, 2003

14

Heme-copper/dioxygen adduct formation relevant to cytochromecoxidase: spectroscopic characterization of [(6L)FeIII-(O22−)-CuII]+

Reza A. Ghiladi, Hong-wei Huang, Pierre Moënne-Loccoz, Jay Stasser, Ninian J. Blackburn, Amina S. Woods, Robert J. Cotter, Christopher D. Incarvito, Arnold L. Rheingold, Kenneth D. Karlin

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2005

Language:

english

File:

PDF, 642 KB

english, 2005

15

Structure and coordination of CuBin theAcidianus ambivalens aa3quinol oxidase heme–copper center

Tiago M. Bandeiras, Manuel M. Pereira, Miguel Teixeira, Pierre Moenne-Loccoz, Ninian J. Blackburn

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2005

Language:

english

File:

PDF, 471 KB

english, 2005

16

Tryptophan Cu(I)–π interaction fine-tunes the metal binding properties of the bacterial metallochaperone CusF

Isabell R. Loftin, Ninian J. Blackburn, Megan M. McEvoy

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2009

Language:

english

File:

PDF, 345 KB

english, 2009

17

The copper centers of tyramine β-monooxygenase and its catalytic-site methionine variants: an X-ray absorption study

Corinna R. Hess, Judith P. Klinman, Ninian J. Blackburn

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

18

Copper transfer to the N-terminal domain of the Wilson disease protein (ATP7B): X-ray absorption spectroscopy of reconstituted and chaperone-loaded metal binding domains and their interaction with exogenous ligands

Martina Ralle, Svetlana Lutsenko, Ninian J. Blackburn

Journal:

Journal of Inorganic Biochemistry

Year:

2004

Language:

english

File:

PDF, 285 KB

english, 2004

19

Introducing unnatural amino acids into protein metal-binding sites and its role in metalloprotein design and engineering

Yi Lu, Steven M. Berry, Mathew D. Gieselman, Martina Ralle, Donald W. Low, Wilfred A. van der Donk, Ninian J. Blackburn

Journal:

Journal of Inorganic Biochemistry

Year:

2003

Language:

english

File:

PDF, 188 KB

english, 2003

20

10.1038/9274

Fee, James A., McRee, Duncan E., Williams, Pamela A., Blackburn, Ninian J., Sanders, Donita, Bellamy, Henry, Stura, Enrico A.

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 1.12 MB

english, 1999

21

Unusual Cu(I)/Ag(I) coordination of Escherichia coli CusF as revealed by atomic resolution crystallography and X-ray absorption spectroscopy

Isabell R. Loftin, Sylvia Franke, Ninian J. Blackburn, Megan M. McEvoy

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 381 KB

english, 2007

22

Isocyanide binding to the copper(I) centers of the catalytic core of peptidylglycine monooxygenase (PHMcc)

Rhames, Francis, Murthy, Narasimha, Karlin, Kenneth, Blackburn, Ninian

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

23

Purification and Characterization of Laccases from the White-Rot BasidiomyceteDichomitus squalens

Frédéric H. Périé, G.Vijay Bhasker Reddy, Ninian J. Blackburn, Michael H. Gold

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 137 KB

english, 1998

24

Large scale production of the copper enzyme peptidylglycine monooxygenase using an automated bioreactor

Andrew T. Bauman, Martina Ralle, Ninian J. Blackburn

Journal:

Protein Expression and Purification

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

25

Dopamine-β-hydroxylase: Evidence for binuclear copper sites

Ninian J. Blackburn, Howard S. Mason, Peter F. Knowles

Journal:

Biochemical and Biophysical Research Communications

Year:

1980

Language:

english

File:

PDF, 391 KB

english, 1980

26

CTR Structure and Mechanism

De Feo, Christopher J., Aller, Stephen G., Barkan, Yariv, Shcushan, Maya, Siluvai, Gnana, Ben-Tal, Nir, Blackburn, Ninian J., Unger, Vinzenz M.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 95 KB

english, 2009

27

The Catalytic Copper of Peptidylglycine α-Hydroxylating Monooxygenase also Plays a Critical Structural Role

Siebert, Xavier, Eipper, Betty A., Mains, Richard E., Prigge, Sean T., Blackburn, Ninian J., Amzel, L. Mario

Journal:

Biophysical Journal

Year:

2005

Language:

english

File:

PDF, 743 KB

english, 2005

28

Metal-Metal Bonding in Biology: EXAFS Evidence for a 2.5 .ANG. Copper-Copper Bond in the CuA Center of Cytochrome Oxidase

Blackburn, Ninian J., Barr, Mary E., Woodruff, William H., van der Ooost, John, de Vries, Simon

Journal:

Year:

1994

Language:

english

File:

PDF, 788 KB

english, 1994

29

X-ray absorption spectroscopy of metal-histidine coordination in metalloproteins. Exact simulation of the EXAFS of tetrabis(imidazole)copper(II) nitrate and other copper-imidazole complexes by the use of a multiple-scattering treatment

Strange, Richard W., Blackburn, Ninian J., Knowles, P. F., Hasnain, S. Samar

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 786 KB

english, 1987

30

Isocyanides as Ligand-Directed Indicators of Cu(I) Coordination in Copper Proteins. Probing the Inequivalence of the Cu(I) Centers in Reduced Dopamine-.beta.-monooxygenase

Reedy, Brian J., Murthy, Narasimha N., Karlin, Kenneth D., Blackburn, Ninian J.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 712 KB

english, 1995

31

Transforming a Blue Copper into a Red Copper Protein: Engineering Cysteine and Homocysteine into the Axial Position of Azurin Using Site-Directed Mutagenesis and Expressed Protein Ligation

Clark, Kevin M., Yu, Yang, Marshall, Nicholas M., Sieracki, Nathan A., Nilges, Mark J., Blackburn, Ninian J., van der Donk, Wilfred A., Lu, Yi

Journal:

Journal of the American Chemical Society

Year:

2010

Language:

english

File:

PDF, 1.77 MB

english, 2010

32

New thermally stable hydroperoxo- and peroxo-copper complexes

Mahroof-Tahir, Mohammad, Murthy, Narasappa Narasimha, Karlin, Kenneth D., Blackburn, Ninian J., Shaikh, Shahid N., Zubieta, Jon

Journal:

Inorganic Chemistry

Year:

1992

Language:

english

File:

PDF, 310 KB

english, 1992

33

Synthesis and X-ray Absorption Spectroscopy Structural Studies of Cu(I) Complexes of HistidylHistidine Peptides: The Predominance of Linear 2-Coordinate Geometry

Himes, Richard A., Park, Ga Young, Barry, Amanda N., Blackburn, Ninian J., Karlin, Kenneth D.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 84 KB

english, 2007

34

The Catalytic Role of the Copper Ligand H172 of Peptidylglycine α-Hydroxylating Monooxygenase: A Kinetic Study of the H172A Mutant †

Evans, John P., Blackburn, Ninian J., Klinman, Judith P.

Journal:

Year:

2006

Language:

english

File:

PDF, 191 KB

english, 2006

35

Peroxo-, Oxo-, and Hydroxo-Bridged Dicopper Complexes: Observation of Exogenous Hydrocarbon Substrate Oxidation

Obias, Honorio V., Lin, Yin, Murthy, N. N., Pidcock, Elna, Solomon, Edward I., Ralle, Martina, Blackburn, Ninian J., Neuhold, Yorck-Michael, Zuberbühler, Andreas D., Karlin, Kenneth D.

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 50 KB

english, 1998

36

Dioxygen-copper reactivity: EXAFS studies of a peroxo-dicopper(II) complex

Blackburn, Ninian J., Strange, Richard W., Cruse, Richard W., Karlin, Kenneth D.

Journal:

Journal of the American Chemical Society

Year:

1987

Language:

english

File:

PDF, 388 KB

english, 1987

37

Oxo- and hydroxo-bridged (porphyrin)iron(III)-copper(II) species as cytochrome c oxidase models: acid-base interconversions and x-ray structure of the Fe(III)-(O2-)-Cu(II) complex

Nanthakumar, Alaganandan, Fox, Stephen, Murthy, Narasimha N., Karlin, Kenneth D., Ravi, Natarajan, Huynh, Boi Hanh, Orosz, Robert D., Day, Edmund P., Hagen, Karl S., Blackburn, Ninian J.

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 302 KB

english, 1993

38

Formation of a copper-dioxygen complex (Cu2-O2) using simple imidazole ligands

Sanyal, Indrajit, Strange, Richard W., Blackburn, Ninian J., Karlin, Kenneth D.

Journal:

Journal of the American Chemical Society

Year:

1991

Language:

english

File:

PDF, 298 KB

english, 1991

39

X-ray absorption studies of the copper-dependent phenylalanine hydroxylase from Chromobacterium violaceum. Comparison of the copper coordination in oxidized and dithionite-reduced enzymes. [Erratum to document cited in CA117(5):43463e]

Blackburn, Ninian J., Strange, Richard W., Carr, Robert T., Benkovic, Stephen J.

Journal:

Year:

1993

Language:

english

File:

PDF, 115 KB

english, 1993

40

Does Superoxide Channel between the Copper Centers in Peptidylglycine Monooxygenase? A New Mechanism Based on Carbon Monoxide Reactivity †

Jaron, Shulamit, Blackburn, Ninian J.

Journal:

Year:

1999

Language:

english

File:

PDF, 964 KB

english, 1999

41

Spectroscopic Characterization of an Engineered Purple Cu A Center in Azurin

Hay, Michael T., Ang, Marjorie C., Gamelin, Daniel R., Solomon, Edward I., Antholine, William E., Ralle, Martina, Blackburn, Ninian J., Massey, Priscilla D., Wang, Xiaotang, Kwon, Angela H., Lu, Yi

Journal:

Inorganic Chemistry

Year:

1998

Language:

english

File:

PDF, 217 KB

english, 1998

42

A Selenocysteine Variant of the Human Copper Chaperone for Superoxide Dismutase. A Se-XAS Probe of Cluster Composition at the Domain 3−Domain 3 Dimer Interface †

Barry, Amanda N., Blackburn, Ninian J.

Journal:

Year:

2008

Language:

english

File:

PDF, 2.78 MB

english, 2008

43

Probing the Role of Axial Methionine in the Blue Copper Center of Azurin with Unnatural Amino Acids

Berry, Steven M., Ralle, Martina, Low, Donald W., Blackburn, Ninian J., Lu, Yi

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003

44

SpaC and NisC, the Cyclases Involved in Subtilin and Nisin Biosynthesis, Are Zinc Proteins †

Okeley, Nicole M., Paul, Moushumi, Stasser, Jay P., Blackburn, Ninian, van der Donk, Wilfred A.

Journal:

Year:

2003

Language:

english

File:

PDF, 272 KB

english, 2003

45

X-ray absorption edge spectroscopy of copper(I) complexes. Coordination geometry of copper(I) in the reduced forms of copper proteins and their derivatives with carbon monoxide

Blackburn, Ninian J., Strange, Richard W., Reedijk, Jan, Volbeda, Anne, Farooq, Amjad, Karlin, Kenneth D., Zubieta, Jon

Journal:

Inorganic Chemistry

Year:

1989

Language:

english

File:

PDF, 1.17 MB

english, 1989

46

XAS Structural Comparisons of Reversibly Interconvertible Oxo- and Hydroxo-Bridged Heme-Copper Oxidase Model Compounds

Fox, Stephen, Nanthakumar, Alaganandan, Wikström, Mårten, Karlin, Kenneth D., Blackburn, Ninian J.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 617 KB

english, 1996

47

Kinetic Mechanism and Intrinsic Isotope Effects for the Peptidylglycine α-Amidating Enzyme Reaction †

Francisco, Wilson A., Merkler, David J., Blackburn, Ninian J., Klinman, Judith P.

Journal:

Year:

1998

Language:

english

File:

PDF, 140 KB

english, 1998

48

Heterobinucleating Ligand-Induced Structural and Chemical Variations in [(L)Fe III −O−Cu II ] + μ-Oxo Complexes

Obias, Honorio V., van Strijdonck, Gino P. F., Lee, Dong-Heon, Ralle, Martina, Blackburn, Ninian J., Karlin, Kenneth D.

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 85 KB

english, 1998

49

X-ray absorption studies of the copper-dependent phenylalanine hydroxylase from Chromobacterium violaceum. Comparison of the copper coordination in oxidized and dithionite-reduced enzymes

Blackburn, Ninian J., Strange, Richard W., Carr, Robert T., Benkovic, Stephen J.

Journal:

Year:

1992

Language:

english

File:

PDF, 750 KB

english, 1992

50

The copper-catalysed oxidation of ascorbic acid by dioxygen. Part 4. The effect of chloride ions on the kinetics and mechanism

Jameson, Reginald F., Blackburn, Ninian J.

Journal:

Journal of the Chemical Society Dalton Transactions

Year:

1982

Language:

english

File:

PDF, 528 KB

english, 1982